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Heart Health

D-Ribose is a simple sugar with a lot of power. It is one of the building blocks for RNA (genetic material) and also the basis for production of adenosine triphosphate, otherwise known as ATP. ATP is the compound we use to supply energy to our skeletal muscle and heart. Every cell in the body uses ATP for processes such as respiration, digestion and tissue regeneration. Our body makes its own D-Ribose from food but this is a slow process and the levels can be considerably depleted in those who exercise at extreme levels or worse, those suffering from cardiovascular issues.

In fact, D Ribose is cited in research as an essential nutrient for protection and recovery in cardio-vascular disease. A study in The European Journal of Heart Failure shows that ribose appears to improve heart function and quality of life among patients by increasing levels and availability of ATP.

In a study cited below, 16 class III-IV, heart failure patients were supplemented with 15 grams of D-Ribose daily for 8 weeks. The results were that D-Ribose supplementation improved the ventilation efficiency in advanced heart failure patients by 16% and Vo2 by 19%.

heart health - heart attack

There is a short amount of time in which you can help repair your body following a heart attack. Ischemia (restricted flow of oxygen/blood) can cause massive depletion of ATP in the heart muscle. Depletion in ATP can result in reduction in diastolic function meaning that the heart takes in less blood when it relaxes.

D-Ribose helps myocardial cells, restoring ATP, increasing contractions and increasing the amount of blood flow into the heart, thus preventing “reperfusion injury” and free-radical damage to the tissue.

Prevention each day would be better.... but it’s a sugar ....

Although ribose is called a sugar, ribose is metabolized in an entirely different way to typical blood raising sugars, such as glucose, fructose, and sucrose. Our bodies use sugars to fuel ATP turnover but while other sugars increase blood glucose levels, and create spikes in insulin secretion and weight gain, ribose does not. On its own, ribose causes a minor decrease in blood sugar levels. When taken with other carbohydrates ribose can actually help modulate blood sugar spiking.

When should you consider D-Ribose supplements?

  • If you want to protect against age-related issues such as deterioration of mitochondria and increased risk of degenerative heart conditions as you grow older.
  • If you take statin drugs, D-Ribose can help with associated myalgia
  • If you are diagnosed with high blood pressure
  • I you are taking positive inotrope drugs (drugs that increase heart function such as Digoxin)
  • If you suffer from arrhythmia
  • If you suffer from angina
  • If you suffer from peripheral vascular disease
  • If you are recovering from cardiac surgery
  • If you want to protect your muscles from high-intensity exercise or strenuous activity

How to I take D-Ribose Supplements?

First of all, it is important to choose a 100% pure, no compromises in production, high quality product such as Sweet Cures High Energy D-Ribose™ . Next, it is important to take a clinically effective dosage (you may wish to discuss this with your health care team who know your situation best). 5 grams equates to a teaspoon of D-Ribose sugar. It can be mixed with water or used in the place of sugar for instance on breakfast cereal. The following broad guidelines that are generally considered effective will help you choose a dosage:

  • 5 grams a day for protecting your heart and muscle health and avoiding muscle pain after strenuous exercise
  • 10-15 grams a day if you suffer from mild-moderate heart failure or peripheral vascular disease
  • 10-15 grams a day for athletes performing intense exercise
  • 10-15 grams a day if you are recovering from a heart attack/heart surgery/ or suffer from stable angina
  • 15-30 grams a day if you suffer from frequent angina/dilated cardiomyopathy/advanced heart failure or are awaiting heart transplant surgery ( THIS MUST BE UNDER MEDICAL SUPERVISION).

Seeking Medical Support

It would be helpful to work with a doctor who knows you well and has researched D Ribose and its amazing benefits. However, if you are pregnant or breastfeeding or suffer from diabetes, you MUST seek support from your healthcare provider before taking a D Ribose supplement.


Int J Cardiol. 2009 Sep 11; 137(1):79-80. doi: 10.1016/j.ijcard.2008.05.025. Epub 2008 Jul 31.

D-Ribose aids advanced ischemic heart failure patients.

MacCarter D

Vijay N

Washam M

Shecterle L

Sierminski H

St Cyr JA

Pauly DF, Pepine CJ. D-Ribose as a supplement for cardiac energy metabolism. J Cardiovasc Pharmacol Ther. 2000 Oct; 5(4):249-58.
Omran, H, et al. D-Ribose improves diastolic function and quality of life in congestive heart failure patients. European J Heart Fail, Vol. 5, No. 5, October 2003, pp. 615-19
MacCarter, D, et al. D-Ribose aids advanced ischemic heart failure patients. International Journal of Cardiology, Vol. 137, No. 1, September 11, 2009, pp. 79-80

Smolenski RT, Raisky O, Slominska EM, et al. Protection from reperfusion injury after cardiac transplantation by inhibition of adenosine metabolism and nucleotide precursor. 2001 Sep 18; 104(12 Suppl 1):I246-52.
Wyatt DA, Ely SW, Lasley RD, et al. Purine-enriched asanguineous cardioplegia retards adenosine triphosphate degradation during ischemia and improves post ischemic ventricular function. J Thorac Cardiovasc Surg. 1989 May; 97(5):771-8

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