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Health & Wellbeing

Benefits of Lactobacillus

Lactobacillus Plantarum

Lactobacillus Plantarum is a species of bacteria which is commonly found in many fermented foods and is also naturally present in human saliva. It is one of many so-called ‘friendly’ bacteria, in that it is non-harmful and has several beneficial uses. It is also able to survive and grow in the gastrointestinal tract and can therefore be used as a probiotic. As well as being key to the fermenting process of foods such as Kimchi, Sauerkraut and sourdough, it also has a range of potential health benefits. Strains of L.Plantarum have been shown to:

  • reduce symptoms of IBS (bloating, flatulence, abdominal pain)
  • assist in the treatment of small intestinal bacterial overgrowth (SIBO)
  • help in maintaining gut permeability and accelerating gut repair after illness
  • reduce allergenicity to foods such as soy flour
  • be beneficial in treating Aids-defining illnesses such as Cryptococcosis

There is also evidence that L. Plantarum may help in the treatment/prevention of depression and dementia by increasing hippocampal brain deprivation factors.


Anderson, Rachel C., et al. Lactobacillus plantarum MB452 enhances the function of the intestinal barrier by increasing the expression levels of genes involved in tight junction formation. BMC microbiology 10.1 (2010): 316.

Ducrotté P, Sawant P, and Jayanthi V (2012) Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome. World J Gastroenterol. 2012 Aug 14; 18(30): 4012-4018.

Frias, J et al. , Immunoreactivity and Amino Acid Content of Fermented Soybean Products. J. Agric. Food Chem., 2008, 56 (1): 99-104

Jung et al, Lactobacillus pentosus var. plantarum C29 protects scopolamine-induced memory deficit in mice. J Appl Microbiol. 2012 Dec;113(6):1498-506.

Silvestri, G et al, Early Mucosal Sensing of SIV Infection by Paneth Cells Induces IL-1β Production and Initiates Gut Epithelial Disruption. PLoS Pathogens, 2014, 10 (8): e1004311

Soifer LO, Peralta D, Dima G, Besasso H. Comparative clinical efficacy of a probiotic vs. an antibiotic in the treatment of patients with intestinal bacterial overgrowth and chronic abdominal functional distension: a pilot study. Acta Gastroenterol Latinoam. 2010; 40:323-327.

Lactobacillus Rhamnosus

Lactobacillus Rhamnosus is a species of beneficial or ‘friendly’ bacteria. It is believed to have a range of health benefits and various strains of L. Rhamnosus are used for probiotics, as well as in dairy products such as yoghurts and un-pasteurised milks.

Certain strains of L. Rhamnosus, such as L. Rhamnosus GG, have been extensively studied and their potential beneficial effects include:

  • Increased weight loss in women
  • Prevention and treatment of diarrhoea and gastrointestinal infections
  • Prevention of respiratory tract infections
  • Treatment of female genitourinary infections such as Bacterial vaginosis
  • Reduction of gut permeability
  • Reduction of peanut allergenicity
  • Enhancing natural immunity

Though L. Rhamnosus is widely considered to be safe and highly beneficial, there is some evidence that, in rare cases, it may cause problems for individuals with weakened immune systems. It should therefore not be taken by people who are severely immunocompromised, unless under medical supervision.


Canani RB et al., Probiotics for treatment of acute diarrhoea in children: randomised clinical trial of five different preparations, BMJ. 2007 Aug 18; 335(7615): 340.

Francavilla, R. et al. A randomized controlled trial of Lactobacillus GG in children with functional abdominal pain, Dec 2010, Paediatrics 126 (6): e1445-52

Gupta, V; Garg, R. Probiotics. Indian Journal of Medical Microbiology 2009, 27 (3): 202-9

Hatakka K, Effect of long term consumption of probiotic milk on infections in children attending day care centres: double blind, randomised trial, BMJ. 2001 Jun 2; 322(7298): 1327.

Ling, H. Systemic Immunity-Enhancing Effects in Healthy Subjects Following Dietary Consumption of the Lactic Acid Bacterium Lactobacillus Rhamnosus HN001. Journal of the American College of Nutrition, 2001, 20 (2):149-56.

Martinez RCR, Improved cure of bacterial vaginosis with single dose of tinidazole (2 g), Lactobacillus Rhamnosus GR-1, and Lactobacillus reuteri RC-14: a randomized, double-blind, placebo-controlled trial, Canadian Journal of Microbiology, 2009, 55(2): 133-138

Tang, MLK et Al, Administration of a probiotic with peanut oral immunotherapy: A randomized trial, Journal of Allergy and Clinical Immunology, March 2015, 135 (3): 737-744.e8

Sanchez M, Effect of Lactobacillus Rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women. Br J Nutr. 2014 Apr 28;111(8):1507-19

Ling, H. Systemic Immunity-Enhancing Effects in Healthy Subjects Following Dietary Consumption of the Lactic Acid Bacterium Lactobacillus Rhamnosus HN001. Journal of the American College of Nutrition, 2001, 20 (2):149-56.


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